I won't be letting this go and I'll be actively pursuing recourse from the manufacturer and vet in any way I can. Now her dog is very sick and she has to take the dog to the vet every day in the past week. Simparica Trio should be given orally once a month at the recommended minimum doses: 0.54 milligrams of sarolaner, 0.011 mlilligrams of moxidectin, and 2.27 milligrams of pyrantel per pound of body weight. #JusticeforCassie My thoughts and prayers are with you all as I go through the same thing with my beautiful Cassie girl. Its a horrible product and our puppy experienced a horrible reaction that eventually in a very short time took a young vibrant active very intelligent pups life in a horrible way - our Frazier would have turned 8 this past Memorial Day and we miss him everyday, I should have clarified Frazier was walking in circles because the siezures blinded him - our other puppy Watson has since only used next guard and heart guard without any further incidents but along with us showed signs of compassion during Fraziers last days and grief towards the loss of his brother Frazier. I was using the garlic tabs for the previous dog because the vet put him on Trifexis and he vomited like crazy. They are monitoring her. His motor skills have been affected and hes been losing weight even though he eats heartily. Please do NOT use it!! Does this sound familiar to anyone? Each month he got sicker and sicker. Random vomitting is no fun either. I lost my dog due to Simparica Trio. Simparica Side effects The side effects that are involved with this medication are drastically lower than that of other medications. We rushed him to the emergency vet and they put him on keppra to stop the seizures. Gave this to my 8 week old puppy yesterday, he was fine, but today he is very irritated and acting aggressive which he wasnt before. Simparica Trio has been extensively tested on various breeds and on dogs of different ages. The only thought in my head was to get home and give it to my puppy who has had few fleas, but many itching problems. Simparica Trio is not effective against adult heartworms. Or has it been too many doses ? He is back to his old self now but we will never give him this medication again. Can blocking GABA receptors also cause inflammation of spine? Follow the directions on the drug label for Simparica or Simparica Trio or as provided by your veterinarian. She had terrible vomiting and diarrhea for a week and also weakness and staggering three weeks later. I not any kind of a medical doctor nor am I a vet however I do often research many topics on health related matters both canine and human for decades and then use my common sense to draw logical conclusions or make reasonable guesses. I took him back to the vet and explained my concern that it was from the Simparica Trio and they didn't seem concerned that it was the issue. Was prescribed Simparica Trio for my Catahula dog with no medical issues. The vet told me to switch to Simparica trio after they stopped seeking revolution which he had been on for many years. I have always been apprehensive about putting my dog on Heartworm / Flea Tick medication because of horror stories, but I thought he's 5 and it will be from the vet and it seems like the responsible thing to do. The office girl not the vet said if it my dog threw up within one hour after eating her pill - then it is safe to give her another one. Although these products can and have been. Initially I noticed minor tremors and twitching when he slept or was just relaxing. Called vet and was advised chicken and rice by tech - vet did not come to the phone even tho I asked to speak to her twice. The active ingredient of Simparica, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. . Other signs may include: Lethargy Loss of appetite It went away. What are the side effects of Simparica trio for dogs? This is just another reason to follow your vet's recommendations for annual physical exams and tests. Vet says garlic doesn't work and obviously it didn't because he shaved a little of dogs fur and put it on a paper towels and it was full of fleas.The vet gives me Simpirica-ok fleas are dropping off him like crazy. Im praying over him too . Eyes roll back. We gave Simparica two days ago and he's not had an appetite, he's eating grass, is drinking a lot of water and sleeping. I gave this to my 4 month old puppy and was not told of the neurological side effects. I am feeding her foods such as spirulina; b12 and a special healing earth in her dinner. Thank you all so much!!!! We tried stopping the simparica. Wonder why PetSmart offers this if there are so many concerns reported. He has been very healthy, and it does not seem to bother him, but it is becoming more noticeable recently. This drug has caused our dog to loose his footing and not eat. She will never have this again, I can assure you! When I bathe him the scabs fall off and I think, oh good, this problem is going away. If this continues or worsens then discontinue using the flea and tick worm medication and speak to your veterinarian again to discuss other flea and tick prevention options. This can help with feelings of anxiety, stress, and fear." We did abx, shampoos changed food. If it has been a long period of time since the last dose was given, you may see fleas temporarily during the missed time. Decreased conscious proprioception. Im seeing an improvement in my dog, and am crossing fingers that this continues! Our 6 year old, 66# Treeing Walker Coon Hound baby has been taking Simparica for about two years. I thought maybe he got into something. My miniature Dash hound did not pull out. I won't sleep until we all get the justice for our babies that don't have voices of their own. He never ever used to do this. I give my dogs Simparica at the beginning of each month. Almost $4k in medical labs, hospital, ultrasound etc no answers. Vet trip and meds $400! Simparica Trio comes with a customer satisfaction guarantee: Zoetis will cover some or all vet expenses should your dog develop heartworm disease, Lyme disease, a flea infestation, hookworms, or roundworms. Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. Once again peed in my office on Saturday. Topical only for me from now on. How common are Simparica side effects? I feel like she's been an experiment to make others money. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. Maybe? He had soft poop right after I give him the pill then got worse yellow diarrhea for about a week also vomiting he fine now they changed the medication. I feel like this drug was pushed by my vet tech and veterinarian. This morning was the first morning he left water in his bowl. How did your baby do please? Side effects with Simparica are not common. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). Please advise! Some pets fare better with topical solutions instead of chewables. If fact it specifically states on the product label "Not for use in humans". But im 99% sure the simparica is what caused it. I have paid about $500 - $600 to heal the little King, but it's not working. We started the medication on Dec. 1st and 3 days later it started with vomiting and loss of appetite. Bentlee has been fine for 12 + hours in the house while I was stuck at work and never a drop of anything in the house. Im so worried Ive lost him forever and hell never recover. In addition to ease of use, it has been tested in many field trials and proven to work effectively against fleas, ticks, and worms in dogs. My 15 yr old doodle wasnt given bravecto because of reviews. We have a 3 month old Aussie labradoodle and the breeder warned against oral flea meds. What You Need to Know About the Lyme Vaccine for Dogs. Over two weeks later she still can not walk properly. They would clear up after a round of antibiotics but would return the next month. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. I gave this for the first time to my hound and about 3 hours later, she was very unsteady on her feet, eyes half shut and then had 4 episodes of breathing rapidly that each lasted 30 seconds or so and all happened within a 30 minute period. This crap is poison! Were there any other conditions? I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is . Im certain that its the simparica. Can you tell me if your dog is back to normal now?!?! Not grass grazing either. His blood work came back normal but the vet called me to ask if his simparica somehow coincided with time of the seizures. Hi, Id like to thank all the contributors to this thread and Im so very sorry for the pain you and your pets have undergone. He has never done this, and when I heard it and woke up he couldn't stop. She still coughs, sneezes and brings up lots of mucus. Saturday he started up the drinking again and threw up his breakfast. This junk needs to be pulled from the market. Hi, how much charcoal did you administer? I take her everywhere as I'm terrified of it happening and her dying, we were convinced she was dying. Possible side effects: Vomiting, diarrhea (if these . Ticks are horrible here in Maine. He is fully housebroken and just had a running stool accident in the house. Then they come back! Stopped meds and he has had 3 more seizures since. After being ingested by a dog, sarolaner is distributed throughout the body. These dog training tips will help you get started. Is Simparica only available with a prescription? But today she isnt eating well, had a bout of diarrhoea and is very tired. I need to tell my vet to switch! How is ur puppy? Does anyone know of anything we can give her to help get this out of her system? Hopefully there are many other dogs that are unaffected, and just aren't written about here. She's pacing and wants to eat grass. But few people read it or think it must be a million to one problem. Hoping you are the lucky ones!! Stay safe! I am trying to remain confident that my poor girl will recover. He is still not himself, walks very slowly and is definitely not feeling his best. I argued with the vet that this is poison and she said why would I give your dog poison? 24 hours later she had another one. Those with Diarrhea symptom, did it look like mucus in their pets stool? Trifexis and Simparica are available only with a prescription from your veterinarian. Did your dog pass away? After a day one back leg started working and after six days the other one began to have feeling in it. I even told them about the Simparica which they dont respond to. Monday, Tuesday, Wednesday and Thursday he slept all day, was hesitant to get up, wouldn't play with his ball, continued to drink excessively and shivered. Sorry, cant see you for 4 days. Will it get worse Will he get better? It is Easter Sunday and he still has diarrhea and drinking a crazy amount of water. My vet is aware of this and prescribed simparica. Then the following week 1 pill every other day . But I noticed that I had to "wake him' several times in only 2 minutes time, but he wasn't sleeping, his eyes were open and I saw them rolling in the back of his head! Sorry man, that is horrible. Simparica Trio covers the most common dog parasites and typically costs less than buying separate products. Use with caution in dogs with a history of seizures or neurologic disorders. Losing my Dolly devastated me and I wanted to warn others about Simparica but I got sick. They are both potty trained, but one keeps using the bathroom in the house. But I have heard of other dogs who recover, or who continue having seizures but not fatal. We think that the drug is the cause of the seizures . Advised I could call Simparica for reimbursement or to report side effects. Thanks all for sharing your experiences. Strictly natural with zero side effects from now on. Any believers out there please say a prayer for our pup as I will for the people on this thread. Do not give extra or double doses. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. Good luck. Be aware! Still waiting on the vet and waiting to talk to ASPCA poison control. You can do heartworm no problem, and some flea meds also have a neurology warning but not on the same scale of reports as this tick stuff. Gave my dog Charlie Simparica yesterday now he is shaking and panting really bad. During this period coincidentally I have noticed a change in his behaviour. 1 dose of this Simperica Trio and he is completely different and cant hold his pee. The excerpts below from the manufacturers' Prescribing . This was the 2nd does I have him. The whole packet is going in the bin !! I am sorry you are going through this! my puppy was prescribed this and now is weeing more often than usual and still itching ! I can not find any information on a delayed reaction AND my Vet just discredits that its the Simparica because my dog goes to Daycare and could be exposed to other mystery things. He was given fluids, anti-nausea meds, meds to assist with the inflammation of his esophagus. This time he is having seizures. My chihuahua is 18 days since the last seizure episode, she is finally playing again but I'm noticing her shaking her head on the left side and it's very odd. Sold as 1 Month, 3 Month or 6 Month Supply for the following dog weights : 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs. This content shouldnt take the place of advice by your vet. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. But this month we are at day 7 and I expect the diarrhea it to continue. I have an 8 year old Labrador. I should have kept with my gut feeling about any of these oral meds. Just after the 4th dose he started to collapse at his feeding dishes on the floor, next we raised dishes and he did ok for being shaky but continued to decline to the point where he could not use dishes , and now cant eat or drink. It was 11:30 pm . Bentlee trusts me an I let him down on this one. We spend last night at the Emergency Vet, and all day today at her normal vet. I feel like the simperica trio has somehow affected his Pituitary/Andrenal glands are maybe even acting as blockers to them. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. Head down, tail down, will stand in a corner and stare at the wall. Simparica may also cause the following side effects: Vomiting Diarrhea Lethargy Contact your veterinarian if your dog experiences any side effects as a result of taking Simparica. Oh how I wish I had know the side effects of this medicine I would never haven given it to her.. the company that makes this poison should be sued. Side effects are uncommon, but may occur in some cases. I wish I could get it out of her system. Moreover, the safe use of this product has not been evaluated in breeding, pregnant or lactating dogs. I notified my vet and Zoetis, the company that makes this drug. Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. Simparica Trio is the first and only product that combines sarolaner, moxidectin and pyrantel in each treatment to help prevent heartworm disease, kill fleas before they can lay eggs, kill 5 types of ticks, treat and prevent flea infestations and treat and control roundworms and hookworms. It may be that he is getting older as he is now one years old and he was neutered about three months ago. She was terrified and we were too. It has a good rating also 4.7 out of 5. I understand them charging for the Euthanasia and cremation but they said they would keep her for 12 hours and she was put down at around 3:00 which was 1/2 the time they agreed on.Now he will get none of the fees back that the company offered for the dogs care, and hey don't have their dog .On top of that they have 3,500.00 vet bills.Why are vets allowed to charge so much?it is more than a person.It really seems as though they don't care about the pets or the people that own them Also why is these types of flea meds still on the market and why is there no legal action available for the poor consumers.I feel like they were legally assaulted by all involved and let us not forget the poor 2 year old rescue dog who ended up having a terrible short life.How unfair. What are the side effects of Simparica Trio Chewable Tablets for Dogs? If you're not already protecting your dog from common disease-causing parasites, then it's time to schedule a visit to your veterinarian. It can also cause seizures and tremors, but those side effects are incredibly rare. All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. I originally wanted to get Nexgard, but for some odd reason, when I had went to my vet to pick it up, instead they gave me this. My dog is experiencing these same symptoms and had his first accident in yearsss in the house and is drinking water excessively. OMG - I am so mad at myself for not doing more research. Vet took blood yesterday should get results today. Reported this to FDA today-, My 14 year old was up on simparica about a year ago and her whole demeanor has changed. all my dogs were prescribed and my eldest dog has had a strange reaction hives all over his body, panting, restless started same night he took the pill but has had the product on previous occasions with no side effects but this time he had a that reaction,had to administer meticam for the pain and antihistamines for the hives - he is still not right after 4 days and my other dog louie has always suffered from seizures since a pup vet say possible epilepsy - managed without medication at present and I do always try to avoid medication with him as they always make his seizures worse - I am so angry for not researching this further before .. I wish I would have came across this before I gave my healthy 9 month old puppy this medication two days ago. and to only let him out on a leash to go potty. We are going back to the Seresto collar next month. It is the flea and tick component that is the problem. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. I regret putting her on this drug. I will not give it to my puppy again, but what is a safer med. Anything I can do for him? This happened the same to my dog.. how si going now with your pet? We trusted our Vet when he recommended this over Revolution topical anti-tic/flea medication. Will be talking to the vet inregards to his side effects. I have written to the parent company that makes Simparico (although I don't hold high hopes that I will ever hear from them) and also signed an online petition at Change. I took my dog to the vet today and she received fluids and gabapentin. He had never pooped in the house and now he does every time he has to be put in his indoor pen for us to leave or sleep. She text me asking if she ever had seizures before. Why the vets use this treatment after so many side effects being reported is disgusting. Omg Im feeling sick seeing all these bad comments. Although vet wanted to treat him for Addison's I decided to wait it out and fortunately it worked out. So I started searching and came across this blog and my heart just sank. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hoursincluding the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. Never happened before. Our dog had her first dose June 1st 2022 - diarrhea, scratching, excessive thirst. Don't trust your vet, do your own research. Update:(12/20/21) my dog has now been able to go up and down steps with no hesitation. Just gave my baby her first dose. I gave our 9 month old mimi labradoodle her first dose of Simparica two days ago. My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. She didn't make it to the next day and died overnight. This simple-to-give oral monthly treatment protects dogs against heartworm disease as well as against ticks and fleas and intestinal worms like roundworms and hookworms. They want another blood draw in 3 weeks to see where she is. Instead it has become a world of greed. Made the pressured in to by a vet to give Simparica Trio. Hi, Im wondering whats going on with your dog now? We have been gradually increasing the dose but it hasnt helped. Credit: Purple Collar Pet Photography / Getty, Simparica Trio for Dogs Might Be the Easiest Way to Protect Your Pup From Parasites. They want $5k to do a spinal tap and MRI. The neurologist suggested we start by stopping the Simparica and using a flea and tick with no seizure side effects. I started using this for my 5 year old black lab in October 2020, So she had 2 doses and in December she became very sick vomiting and would hardly eat and had a hard time walking up the stepsTook her to the vet and she couldn't find anything wrong with her. Hi, my dog is having these same issues right now and Im dying. I am so mad at myself and so upset that I am the one that has made him sick. Im a new pet owner and this will sound ignorant Im sure but I had NO IDEA this is how flea meds works and completely trusted my vet who knows my dogs past sensitive history and I was given the drug not even in its package so I could read anything about it but in individual pills. And he was on Comfortis before and did fine. Its crazy to think they dont recover and can die in a few months. Very "out of it". Will not eat or drink. The king cavalier bichon mix seems to be ok just not eating much if at all. This medication should be banned and the company held responsible. This morning I caught him chewing the end of his tail and eating his fur. Would you mind sharing what happened with your pup? He would come out of it when I shook him, so I didn't think anything of it at the time. Furious that this out there for pets. Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. I gave my dog simparica at 10:15am. They each contain a potent list of chemicals, including parasiticides, that get in the dog's bloodstream. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. Also I read on Dr Mercola site that heartworms is in the dogs blood not the digestive track and garlic won't work. The initial trial had seizure results but supposedly only in dogs with seizure history. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. Hi Chelsea, I am hopeful that your Shepherd has recovered. But now I tell everyone just be aware that this product does have the potential to cause neurological harm. The next day Bellas stools were quite soft but still had some structure. We are already close to $2000 in Vet bills not counting the poison we bought her. A week after I lost her I got COVID and was in the hospital for 20 days. iI hope she will not have any other problems. Use topical or a collar if you are concerned. Zoetis claims it will be out of his system in two months and I should not see lasting effects, so I am hopeful but worried and telling everyone I know NOT to use this poison. we gave our dane Simperica Brown about a day or so ago and all the sudden my sweet girl is having seizures. And has been for about 3 weeks. He seems back to his normal self and playing with his toys, but we will not continue the following doses! Simparicaworks by impacting the nervous system of invertebrates such as fleas and ticks. This medicine is making her shaky/tremor, anxious, and she is panting a ton. Hi Laura, How is you pup doing one after getting off simparica? Been also very lethargic not wanting to get out of bed. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. We can give her to help get this out of 5 may be that he fully. Voices of their own ago and her dying, we were convinced she dying. Only let him out on a leash to go up the drinking and. 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Hes been losing weight even though he eats heartily will never have this again, but it hasnt helped other!
